Preorganization of the hydroxyethylene dipeptide isostere: the preferred conformation in solution resembles the conformation bound to BACE. [electronic resource]
Producer: 20060209Description: 7623-7 p. digitalISSN:- 0022-2623
- Amyloid Precursor Protein Secretases
- Aspartic Acid Endopeptidases
- Crystallography, X-Ray
- Dipeptides -- chemistry
- Endopeptidases -- chemistry
- Humans
- Leucine -- chemistry
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Molecular Conformation
- Phenylalanine -- chemistry
- Protease Inhibitors -- chemistry
- Solutions
- Valine -- chemistry
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Publication Type: Journal Article
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