SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells. [electronic resource]
Producer: 20060118Description: 10381-8 p. digitalISSN:- 0008-5472
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- antagonists & inhibitors
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- Drug Synergism
- Female
- Humans
- Mice
- Microtubules -- drug effects
- Ovarian Neoplasms -- drug therapy
- Paclitaxel -- pharmacology
- Protein Isoforms
- Tubulin -- biosynthesis
- Up-Regulation
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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