Essential role of the imidazoline moiety in the insulinotropic effect but not the KATP channel-blocking effect of imidazolines; a comparison of the effects of efaroxan and its imidazole analogue, KU14R. [electronic resource]
Producer: 20060216Description: 2567-75 p. digitalISSN:- 0012-186X
- Action Potentials -- drug effects
- Animals
- Benzofurans -- chemistry
- Calcium -- metabolism
- Cell Line
- Cytosol -- metabolism
- Imidazoles -- chemistry
- Imidazolines -- chemistry
- Insulin -- metabolism
- Insulin Secretion
- Insulin-Secreting Cells -- drug effects
- Membrane Potentials -- drug effects
- Mice
- Mice, Mutant Strains
- Patch-Clamp Techniques
- Potassium Channel Blockers -- pharmacology
- Potassium Channels -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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