Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress. [electronic resource]
Producer: 20060112Description: 17207-12 p. digitalISSN:- 0027-8424
- Adenocarcinoma -- drug therapy
- Adherens Junctions -- drug effects
- Animals
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Aspirin -- administration & dosage
- Caspase 3
- Caspases -- biosynthesis
- Cell Line, Tumor
- Colonic Neoplasms -- drug therapy
- Cyclin D1 -- metabolism
- Down-Regulation -- drug effects
- Genes, APC
- Humans
- Hydrolysis
- Mice
- Mice, Inbred C57BL
- Nitric Oxide Donors -- administration & dosage
- Oxidative Stress -- drug effects
- Signal Transduction -- drug effects
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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