4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors. [electronic resource]
Producer: 20060302Description: 280-4 p. digitalISSN:- 0960-894X
- Administration, Oral
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides -- drug effects
- Animals
- Aspartic Acid Endopeptidases
- Brain -- drug effects
- Cyclohexanes -- administration & dosage
- Dose-Response Relationship, Drug
- Endopeptidases -- drug effects
- Enzyme Inhibitors -- chemical synthesis
- Mice
- Molecular Structure
- Peptide Fragments -- drug effects
- Structure-Activity Relationship
- Sulfones -- administration & dosage
- Time Factors
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Publication Type: Journal Article
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