Stimulation of PGE receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following beta-amyloid exposure. [electronic resource]
Producer: 20060117Description: 2199-206 p. digitalISSN:- 0953-816X
- Adenosine Diphosphate -- pharmacology
- Alprostadil -- analogs & derivatives
- Amyloid beta-Peptides -- toxicity
- Animals
- Animals, Newborn
- Blotting, Western -- methods
- Cell Death -- drug effects
- Cell Survival -- drug effects
- Cerebral Cortex -- cytology
- Dinoprostone -- analogs & derivatives
- Dose-Response Relationship, Drug
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- L-Lactate Dehydrogenase -- metabolism
- Mice
- Mice, Inbred C57BL
- Neurons -- drug effects
- Oxidative Stress -- drug effects
- Peptide Fragments -- toxicity
- Receptors, Prostaglandin E -- physiology
- Receptors, Prostaglandin E, EP2 Subtype
- Receptors, Prostaglandin E, EP4 Subtype
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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