In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant. [electronic resource]
Producer: 20051219Description: 9510-6 p. digitalISSN:- 0008-5472
- Animals
- Blotting, Western
- Colonic Neoplasms -- drug therapy
- Cytidine Deaminase
- Deoxycytidine -- analogs & derivatives
- Deoxycytidine Kinase -- biosynthesis
- Deoxycytosine Nucleotides -- metabolism
- Drug Resistance, Neoplasm
- Female
- Gene Expression Profiling
- Mice
- Mice, Inbred BALB C
- Nucleoside Deaminases -- biosynthesis
- Oligonucleotide Array Sequence Analysis
- Protein Subunits
- Ribonucleotide Reductases -- biosynthesis
- Gemcitabine
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Publication Type: Journal Article
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