Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses. [electronic resource]
Producer: 20051219Description: 9479-84 p. digitalISSN:- 0008-5472
- Animals
- Chlorocebus aethiops
- DNA, Viral -- biosynthesis
- Enzyme Activation
- Gene Expression Regulation, Viral -- radiation effects
- HeLa Cells
- Herpesvirus 1, Human -- enzymology
- Humans
- MAP Kinase Signaling System
- Mice
- Neoplasms -- therapy
- Pancreatic Neoplasms -- therapy
- Phosphorylation
- Promoter Regions, Genetic -- radiation effects
- Rabbits
- Up-Regulation -- radiation effects
- Vero Cells
- Xenograft Model Antitumor Assays
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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