Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability. [electronic resource]
Producer: 20051104Description: 719-29 p. digitalISSN:- 0007-0920
- Allelic Imbalance
- Antigens, Neoplasm -- genetics
- Aurora Kinase A
- Aurora Kinase B
- Aurora Kinases
- Biomarkers, Tumor -- metabolism
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung -- enzymology
- Catalytic Domain
- DNA-Binding Proteins -- genetics
- Epithelial Cells -- metabolism
- Gene Expression Regulation, Enzymologic
- Genes, Tumor Suppressor
- Humans
- Lung Neoplasms -- enzymology
- Microsatellite Repeats
- Polymorphism, Restriction Fragment Length
- Protein Serine-Threonine Kinases -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Serine Proteinase Inhibitors -- genetics
- Serpins -- genetics
- Telomerase -- genetics
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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