Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase. [electronic resource]
Producer: 20051202Description: 1222-8 p. digitalISSN:- 0301-472X
- Amino Acid Substitution
- Animals
- Cell Line, Tumor
- Fusion Proteins, bcr-abl
- Hematopoietic Stem Cells -- metabolism
- Humans
- Immunoprecipitation -- methods
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- genetics
- Mice
- Mutagenesis, Site-Directed
- Philadelphia Chromosome
- Phosphatidylinositol 3-Kinases -- genetics
- Point Mutation -- genetics
- Protein Binding
- Protein Subunits -- genetics
- Protein-Tyrosine Kinases -- genetics
- Proto-Oncogene Proteins -- genetics
- Signal Transduction
- src Homology Domains -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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