The neurotoxic carboxy-terminal fragment of the Alzheimer amyloid precursor binds specifically to a neuronal cell surface molecule: pH dependence of the neurotoxicity and the binding. [electronic resource]
Producer: 19920605Description: 1679-87 p. digitalISSN:- 0270-6474
- Alzheimer Disease -- metabolism
- Amyloid beta-Protein Precursor -- antagonists & inhibitors
- Animals
- Cell Differentiation
- Cell Line, Transformed
- Cell Membrane -- metabolism
- Culture Media
- Hydrogen-Ion Concentration
- Mutation
- Nerve Growth Factors -- pharmacology
- Nervous System -- drug effects
- Neurons -- metabolism
- PC12 Cells -- metabolism
- Peptide Fragments -- metabolism
- Tachykinins -- pharmacology
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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