NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype. [electronic resource]
Producer: 20051230Description: 305-8 p. digitalISSN:- 0300-2977
- Acetylmuramyl-Alanyl-Isoglutamine -- administration & dosage
- Alleles
- Case-Control Studies
- Crohn Disease -- genetics
- Gene Expression Regulation
- Genetic Predisposition to Disease
- Homozygote
- Humans
- Interleukin-1 -- biosynthesis
- Intracellular Signaling Peptides and Proteins -- genetics
- Leukocytes, Mononuclear -- immunology
- Lipopeptides
- Mutation
- Nod2 Signaling Adaptor Protein
- Oligopeptides -- administration & dosage
- Peptidoglycan -- administration & dosage
- Polymerase Chain Reaction
- Signal Transduction -- genetics
- Toll-Like Receptor 2 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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