Genetic time-series analysis identifies a major QTL for in vivo alcohol metabolism not predicted by in vitro studies of structural protein polymorphism at the ADH1B or ADH1C loci. [electronic resource]
Producer: 20060123Description: 509-24 p. digitalISSN:- 0001-8244
- Adolescent
- Adult
- Age Factors
- Alcohol Dehydrogenase -- genetics
- Alcoholism -- blood
- Chromosomes, Human, Pair 14 -- genetics
- Diseases in Twins -- genetics
- Ethanol -- blood
- Female
- Genetic Linkage
- Genetic Variation
- Haplotypes
- Humans
- Male
- Microsatellite Repeats
- Models, Genetic
- Polymorphism, Single Nucleotide -- genetics
- Quantitative Trait Loci -- genetics
- Sex Factors
- Twins, Dizygotic -- genetics
- Twins, Monozygotic -- genetics
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Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Twin Study
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