Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. [electronic resource]
Producer: 20051128Description: 4593-602 p. digitalISSN:- 0022-1767
- Animals
- CD4-Positive T-Lymphocytes -- metabolism
- Down-Regulation -- genetics
- Genetic Predisposition to Disease
- Giant Cells, Langhans -- immunology
- Inflammation -- immunology
- Interferon-gamma -- antagonists & inhibitors
- Interleukin-10 -- biosynthesis
- Mice
- Mycobacterium tuberculosis -- immunology
- T-Box Domain Proteins
- Transcription Factors -- deficiency
- Tuberculosis, Pulmonary -- genetics
- Up-Regulation -- genetics
- T-bet Transcription Factor
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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