Loss of ER retention and sequestration of the wild-type ELOVL4 by Stargardt disease dominant negative mutants. [electronic resource]
Producer: 20060413Description: 657-64 p. digitalISSN:- 1090-0535
- Animals
- Blotting, Western
- COS Cells -- metabolism
- Centrifugation, Density Gradient
- Chlorocebus aethiops
- Endoplasmic Reticulum -- metabolism
- Endoplasmic Reticulum Chaperone BiP
- Eye Proteins -- genetics
- Gene Expression
- Heat-Shock Proteins -- metabolism
- Humans
- Kidney -- embryology
- Macular Degeneration -- genetics
- Membrane Proteins -- genetics
- Microscopy, Fluorescence
- Molecular Chaperones -- metabolism
- Recombinant Fusion Proteins -- genetics
- Transcription Factor CHOP -- metabolism
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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