Lovastatin inhibits the growth and survival pathway of phosphoinositide 3-kinase/protein kinase B in immortalized rat brain neuroblasts. [electronic resource]
Producer: 20050922Description: 1277-87 p. digitalISSN:- 0022-3042
- Androstadienes -- pharmacology
- Animals
- Apoptosis -- drug effects
- Cell Division -- drug effects
- Cell Line, Transformed
- Cell Survival -- drug effects
- Chromones -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Eukaryotic Initiation Factor-4E -- metabolism
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Lovastatin -- pharmacology
- Morpholines -- pharmacology
- Nerve Tissue Proteins -- metabolism
- Neurons -- cytology
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt
- Rats
- Ribosomal Protein S6 Kinases, 70-kDa -- antagonists & inhibitors
- Stem Cells -- cytology
- Tyrosine -- metabolism
- Wortmannin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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