Poly (D,L-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord. [electronic resource]
Producer: 20060227Description: 430-42 p. digitalISSN:- 0142-9612
- Animals
- Axons -- chemistry
- Blood Vessels -- physiology
- Cell Enlargement -- drug effects
- Cell Survival -- drug effects
- Chondroitin Sulfates -- metabolism
- Culture Media, Conditioned -- pharmacology
- Female
- Ganglia, Spinal -- cytology
- Glial Fibrillary Acidic Protein -- analysis
- Green Fluorescent Proteins -- genetics
- Guided Tissue Regeneration -- methods
- Hindlimb -- drug effects
- Implants, Experimental
- Lactic Acid -- chemistry
- Neovascularization, Physiologic
- Nerve Fibers, Myelinated -- physiology
- Nerve Growth Factors -- genetics
- Nerve Regeneration
- Neurotrophin 3 -- genetics
- Polyesters
- Polymers -- chemistry
- Rats
- Rats, Inbred F344
- Schwann Cells -- cytology
- Spinal Cord -- metabolism
- Spinal Cord Injuries -- pathology
- Thoracic Vertebrae
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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