Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor. [electronic resource]
Producer: 20060209Description: 808-16 p. digitalISSN:- 0168-8278
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Ligands
- Liver Neoplasms -- metabolism
- Membrane Potentials -- drug effects
- Receptors, GABA-A -- metabolism
- Signal Transduction -- physiology
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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