Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. [electronic resource]
Producer: 20050927Description: 5175-90 p. digitalISSN:- 0022-2623
- Amyloid Precursor Protein Secretases
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Binding Sites
- Cathepsin D -- antagonists & inhibitors
- Crystallography, X-Ray
- Cyclopentanes -- chemical synthesis
- Endopeptidases
- Furans -- chemical synthesis
- Humans
- Models, Molecular
- Molecular Mimicry
- Peptides -- chemistry
- Pyrrolidines -- chemical synthesis
- Pyrrolidinones -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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