Cathepsins and BID are involved in the molecular switch between apoptosis and autophagy in breast cancer MCF-7 cells exposed to camptothecin. [electronic resource]
Producer: 20071206Description: 159-79 p. digitalISSN:- 1899-1505
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Autophagy -- drug effects
- BH3 Interacting Domain Death Agonist Protein -- metabolism
- Beclin-1
- Breast Neoplasms -- enzymology
- Camptothecin -- pharmacology
- Cathepsin B -- antagonists & inhibitors
- Cell Line, Tumor
- Cysteine Proteinase Inhibitors -- pharmacology
- Enzyme Activation
- Female
- Humans
- Kinetics
- Laser Scanning Cytometry
- Leucine -- analogs & derivatives
- Membrane Proteins -- metabolism
- Microscopy, Confocal
- Microscopy, Electron, Transmission
- Microtubule-Associated Proteins -- metabolism
- Mitochondria -- drug effects
- Signal Transduction -- drug effects
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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