Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism. [electronic resource]
Producer: 20050923Description: 881-8 p. digitalISSN:- 1529-2908
- Animals
- Apoptosis
- Cell Differentiation -- immunology
- Cell Line
- Cell Size
- Cell Survival
- DNA-Binding Proteins -- deficiency
- Glucose -- metabolism
- Glycolysis
- Intracellular Signaling Peptides and Proteins
- Ligands
- Membrane Proteins -- metabolism
- Mice
- Mice, Knockout
- Phosphatidylinositol 3-Kinases -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Receptor, Notch1
- Receptors, Antigen, T-Cell, alpha-beta -- metabolism
- Receptors, Cell Surface -- metabolism
- Signal Transduction
- T-Lymphocytes -- cytology
- Transcription Factors -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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