Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways. [electronic resource]
Producer: 20050909Description: 7181-92 p. digitalISSN:- 0270-7306
- Animals
- Antigens, CD -- biosynthesis
- Antigens, Differentiation -- metabolism
- Blotting, Western
- CD47 Antigen
- Chromones -- pharmacology
- Cytokines -- metabolism
- Dose-Response Relationship, Drug
- Hydrogen Peroxide -- metabolism
- Immunoprecipitation
- Intracellular Signaling Peptides and Proteins -- metabolism
- Janus Kinase 2
- Macrophages -- metabolism
- Membrane Glycoproteins -- metabolism
- Models, Biological
- Morpholines -- pharmacology
- NADPH Oxidases -- metabolism
- NF-kappa B -- metabolism
- Nitric Oxide -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Protein Binding
- Protein Transport
- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Protein Tyrosine Phosphatase, Non-Receptor Type 6
- Protein Tyrosine Phosphatases -- metabolism
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Rats
- Reactive Oxygen Species
- Receptors, Immunologic -- metabolism
- Recombinant Fusion Proteins -- metabolism
- Respiratory Burst
- Signal Transduction
- Thymus Gland -- metabolism
- Time Factors
- rac1 GTP-Binding Protein -- metabolism
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Publication Type: Journal Article
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