Suppression of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis by pre-initiation treatment of rats with beta-naphthoflavone coincides with decreased levels of the carcinogen-derived DNA adducts in the mammary gland. [electronic resource]
Producer: 20060411Description: 338-47 p. digitalISSN:- 0361-090X
- 9,10-Dimethyl-1,2-benzanthracene -- analogs & derivatives
- Adenocarcinoma -- chemically induced
- Animals
- Carcinogens -- antagonists & inhibitors
- Cytochrome P-450 Enzyme System -- drug effects
- DNA Adducts -- drug effects
- Disease Models, Animal
- Enzyme Induction -- drug effects
- Enzyme Inhibitors -- administration & dosage
- Female
- Glucuronosyltransferase -- drug effects
- Glutathione Transferase -- drug effects
- Liver -- drug effects
- Mammary Glands, Animal -- drug effects
- Mammary Neoplasms, Experimental -- chemically induced
- Rats
- Rats, Sprague-Dawley
- beta-Naphthoflavone -- administration & dosage
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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