Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat. [electronic resource]
Producer: 20060309Description: 119-26 p. digitalISSN:- 0969-9961
- Animals
- Animals, Newborn
- Apoptosis -- drug effects
- Biomarkers
- Calpain -- metabolism
- Caspase 1 -- metabolism
- Caspase 3
- Caspases -- metabolism
- Cytochromes c -- metabolism
- Enzyme Activation -- drug effects
- Gene Expression -- drug effects
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Hypoxia-Ischemia, Brain -- drug therapy
- Intercellular Adhesion Molecule-1 -- genetics
- Interleukin-1 -- genetics
- Nerve Degeneration -- drug therapy
- Poly(ADP-ribose) Polymerases -- metabolism
- RNA, Messenger -- analysis
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- Simvastatin -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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