hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation. [electronic resource]
Producer: 20050915Description: 6436-53 p. digitalISSN:- 0270-7306
- Animals
- Base Sequence
- Binding Sites
- Cell Transformation, Neoplastic -- metabolism
- Eukaryotic Initiation Factor-4E -- genetics
- Gene Expression Regulation, Neoplastic -- physiology
- HeLa Cells
- Heterogeneous-Nuclear Ribonucleoprotein K -- physiology
- Humans
- Mice
- Molecular Sequence Data
- Promoter Regions, Genetic -- physiology
- Rats
- TATA Box -- genetics
- Transcription, Genetic -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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