Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets. [electronic resource]
Producer: 20051215Description: 3410-4 p. digitalISSN:- 0006-4971
- Blood Platelets -- metabolism
- Cells, Cultured
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Female
- Humans
- MAP Kinase Signaling System -- drug effects
- Male
- Phosphorylation -- drug effects
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- pharmacology
- Platelet Glycoprotein GPIb-IX Complex -- metabolism
- Receptors, Fibrinogen -- metabolism
- Thromboxane A2 -- metabolism
- src-Family Kinases -- antagonists & inhibitors
- von Willebrand Factor -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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