Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia. [electronic resource]
Producer: 20051223Description: 537-45 p. digitalISSN:- 1019-6439
- Antigens, CD -- genetics
- Apoptosis -- drug effects
- Arsenic Trioxide
- Arsenicals -- pharmacology
- Caspase 8
- Caspase 9
- Caspases -- genetics
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Flow Cytometry
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Intracellular Membranes -- drug effects
- Leukemia, Megakaryoblastic, Acute -- genetics
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- Oligonucleotide Array Sequence Analysis -- methods
- Oxides -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Messenger -- genetics
- Receptors, Cell Surface -- genetics
- Receptors, Nerve Growth Factor -- genetics
- Receptors, Tumor Necrosis Factor -- genetics
- Signal Transduction -- drug effects
- Time Factors
- Tumor Necrosis Factor Receptor Superfamily, Member 9
- fas Receptor -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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