Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2. [electronic resource]
Producer: 20051114Description: 901-6 p. digitalISSN:- 0306-4522
- Animals
- Blotting, Western -- methods
- Brain Infarction -- pathology
- Brain Ischemia -- drug therapy
- Cell Count -- methods
- Dose-Response Relationship, Drug
- Fluorobenzenes -- administration & dosage
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- administration & dosage
- Infarction, Middle Cerebral Artery -- etiology
- Laser-Doppler Flowmetry -- methods
- Male
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Nitric Oxide Synthase -- metabolism
- Nitric Oxide Synthase Type II
- Nitric Oxide Synthase Type III
- Pyrimidines -- administration & dosage
- Reperfusion -- methods
- Rosuvastatin Calcium
- Staining and Labeling
- Sulfonamides -- administration & dosage
- Time Factors
No physical items for this record
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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