Transgenic mice expressing the T cell antigen receptor specific for an immunodominant epitope of a major allergen of house dust mite develop an asthmatic phenotype on exposure of the airways to allergen. [electronic resource]
Producer: 20060130Description: 960-9 p. digitalISSN:- 0954-7894
- Animals
- Antigens, Dermatophagoides -- immunology
- Arthropod Proteins
- Asthma -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- Cell Division -- immunology
- Cells, Cultured
- Cysteine Endopeptidases
- Disease Models, Animal
- Dose-Response Relationship, Immunologic
- Goblet Cells -- immunology
- Hyperplasia
- Immunodominant Epitopes -- immunology
- Immunohistochemistry -- methods
- Interleukin-4 -- immunology
- Lung -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mucins -- immunology
- Phenotype
- Receptors, Antigen, T-Cell -- immunology
- Th2 Cells -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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