Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. [electronic resource]
Producer: 20051026Description: 10070-5 p. digitalISSN:- 0027-8424
- Animals
- Calorimetry
- Chalcone -- analogs & derivatives
- Chalcones
- Cloning, Molecular
- Cysteine -- genetics
- DNA-Binding Proteins -- genetics
- Dinitrobenzenes -- metabolism
- Electrophoretic Mobility Shift Assay
- Enzyme Induction -- physiology
- Humans
- Immunologic Factors -- metabolism
- Intracellular Signaling Peptides and Proteins
- Iodoacetamide -- metabolism
- Isothiocyanates
- Kelch-Like ECH-Associated Protein 1
- Models, Molecular
- Multiprotein Complexes -- metabolism
- NF-E2-Related Factor 2
- Prostaglandin D2 -- analogs & derivatives
- Protein Binding
- Protein Structure, Tertiary
- Proteins -- genetics
- Sulfoxides
- Thiocyanates -- metabolism
- Trans-Activators -- genetics
- Vitamin K 3 -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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