Deletion of the beta 2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation. [electronic resource]
Producer: 20061006Description: 314-27 p. digitalISSN:- 0033-3158
- Animals
- Body Temperature -- drug effects
- Brain -- drug effects
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacokinetics
- Chromosome Deletion
- Genotype
- Heterozygote
- Infusions, Intravenous
- Injections, Intravenous
- Maze Learning -- drug effects
- Mice
- Mice, Inbred C57BL
- Motor Activity -- drug effects
- Mutation
- Nicotine -- pharmacology
- Nicotinic Agonists -- pharmacokinetics
- Pyridines -- pharmacokinetics
- Receptors, Nicotinic -- genetics
- Tobacco Use Disorder -- genetics
- Up-Regulation -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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