Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis. [electronic resource]
Producer: 20050915Description: 9417-29 p. digitalISSN:- 0006-2960
- Allosteric Regulation
- Allosteric Site
- Animals
- Catalysis
- Crystallography, X-Ray
- Enzyme Reactivators -- chemistry
- Enzyme Stability
- Fructosediphosphates -- chemistry
- Humans
- Kinetics
- Ligands
- Models, Molecular
- Neoplasm Proteins -- antagonists & inhibitors
- Oxalic Acid -- chemistry
- Protein Conformation
- Protein Structure, Tertiary
- Pyruvate Kinase -- antagonists & inhibitors
- Rabbits
- Saccharomyces cerevisiae Proteins -- chemistry
- Substrate Specificity
- Thermodynamics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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