Role of 5'-nucleotidase in thiopurine metabolism: enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment. [electronic resource]
Producer: 20051222Description: 95-103 p. digitalISSN:- 0009-8981
- 5'-Nucleotidase -- metabolism
- Child
- Chromatography, High Pressure Liquid
- Guanosine Monophosphate -- blood
- Humans
- Hydrogen-Ion Concentration
- Kinetics
- Mercaptopurine -- pharmacology
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Substrate Specificity
- Sulfhydryl Compounds -- chemistry
- Thioguanine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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