Dieldrin induces ubiquitin-proteasome dysfunction in alpha-synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death. [electronic resource]
Producer: 20051128Description: 69-79 p. digitalISSN:- 0022-3565
- Animals
- Apoptosis -- drug effects
- Caspase 3
- Caspases -- metabolism
- Cell Line
- DNA Fragmentation -- drug effects
- Dieldrin -- toxicity
- Dopamine -- physiology
- Dose-Response Relationship, Drug
- Insecticides -- toxicity
- Neurons -- drug effects
- Oxidative Stress
- Parkinsonian Disorders -- chemically induced
- Phagosomes -- drug effects
- Proteasome Endopeptidase Complex -- physiology
- Rats
- Ubiquitin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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