Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. [electronic resource]
Producer: 20050919Description: 483-92 p. digitalISSN:- 0161-6412
- Animals
- Antioxidants -- therapeutic use
- Antipyrine -- analogs & derivatives
- Aspirin -- therapeutic use
- Blotting, Western -- methods
- Brain Edema -- drug therapy
- Brain Ischemia -- complications
- Cerebral Infarction -- prevention & control
- Clopidogrel
- Cyclic AMP Response Element-Binding Protein -- metabolism
- DNA Fragmentation -- drug effects
- Disability Evaluation
- Dose-Response Relationship, Drug
- Drug Administration Routes
- Edaravone
- Functional Laterality
- Gene Expression Regulation -- drug effects
- Hypoxia, Brain -- etiology
- Male
- PTEN Phosphohydrolase
- Phosphoric Monoester Hydrolases -- metabolism
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Rats
- Rats, Sprague-Dawley
- Ticlopidine -- analogs & derivatives
- Tumor Suppressor Proteins -- metabolism
- bcl-2-Associated X Protein
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Publication Type: Comparative Study; Journal Article
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