Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells. [electronic resource]
Producer: 20051213Description: 2660-70 p. digitalISSN:- 0888-8809
- Breast Neoplasms -- genetics
- Bromodeoxyuridine -- metabolism
- Enzyme Activation
- Epidermal Growth Factor -- antagonists & inhibitors
- ErbB Receptors -- metabolism
- Estradiol -- pharmacology
- Estrogen Receptor alpha -- genetics
- Genes, Reporter
- Humans
- Luciferases -- analysis
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- STAT5 Transcription Factor -- antagonists & inhibitors
- Signal Transduction
- Transcription, Genetic
- Transfection
- Tumor Cells, Cultured
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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