Oncogenic Ras blocks transforming growth factor-beta-induced cell-cycle arrest by degradation of p27 through a MEK/Erk/SKP2-dependent pathway. [electronic resource]
Producer: 20050919Description: 747-57 p. digitalISSN:- 0301-472X
- Animals
- Base Sequence
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p27
- DNA Mutational Analysis
- Electroporation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Flow Cytometry
- Genes, ras
- HL-60 Cells
- Humans
- Mice
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- RNA Interference
- Recombinant Proteins -- metabolism
- S-Phase Kinase-Associated Proteins -- metabolism
- Signal Transduction -- drug effects
- Transfection
- Transforming Growth Factor beta -- antagonists & inhibitors
- Tumor Suppressor Proteins -- genetics
- ras Proteins -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.