GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis. [electronic resource]
Producer: 20050916Description: 215-22 p. digitalISSN:- 1019-6439
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Blotting, Western
- Camptothecin -- pharmacology
- Carcinoma, Hepatocellular -- pathology
- Caspase 3
- Caspase 8
- Caspases -- metabolism
- Cell Line, Tumor
- Chromones -- pharmacology
- Cytochromes c -- metabolism
- DNA Fragmentation
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Etoposide -- pharmacology
- Flow Cytometry
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Morpholines -- pharmacology
- Mutation
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Receptors, TNF-Related Apoptosis-Inducing Ligand
- Receptors, Tumor Necrosis Factor -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Serine -- chemistry
- Transfection
- Tumor Suppressor Protein p53 -- metabolism
- fas Receptor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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