The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions. [electronic resource]
Producer: 20050721Description: 730-6 p. digitalISSN:- 1529-2908
- Acid Anhydride Hydrolases
- Animals
- B-Lymphocytes -- immunology
- Base Sequence
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Chickens
- DNA Repair Enzymes -- genetics
- DNA, Neoplasm -- chemistry
- DNA-Binding Proteins -- genetics
- Gene Conversion -- genetics
- Humans
- Immunoglobulin Variable Region -- genetics
- MRE11 Homologue Protein
- Molecular Sequence Data
- Multiprotein Complexes -- genetics
- Nuclear Proteins -- genetics
- Nucleoside Deaminases -- immunology
- Polymerase Chain Reaction
- Recombination, Genetic
- Sequence Alignment
- Sequence Analysis, DNA
- Somatic Hypermutation, Immunoglobulin -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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