A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes. [electronic resource]
Producer: 20050929Description: 1070-6 p. digitalISSN:- 0960-9822
- Bromobenzenes -- chemical synthesis
- Chromosome Segregation -- drug effects
- DNA Primers
- Dimethyl Sulfoxide
- Dose-Response Relationship, Drug
- Kinetochores -- metabolism
- Microarray Analysis
- Microtubules -- metabolism
- Mitosis -- physiology
- Phenotype
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Saccharomyces cerevisiae -- physiology
- Saccharomyces cerevisiae Proteins -- antagonists & inhibitors
- Spindle Apparatus -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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