The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line. [electronic resource]
Producer: 20050728Description: 4929-38 p. digitalISSN:- 0008-5472
- Animals
- Benzoquinones
- Bone Neoplasms -- prevention & control
- Breast Neoplasms -- drug therapy
- Cell Growth Processes -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Chemotaxis -- drug effects
- Disease Models, Animal
- Female
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Lactams, Macrocyclic
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Transplantation
- Osteoclasts -- drug effects
- Rifabutin -- analogs & derivatives
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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