Activation of protein kinase C alpha is required for TPA-triggered ERK (MAPK) signaling and growth inhibition of human hepatoma cell HepG2. [electronic resource]
Producer: 20050923Description: 289-96 p. digitalISSN:- 1021-7770
- Blotting, Western
- Carcinoma, Hepatocellular -- enzymology
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Proliferation
- Cyclin-Dependent Kinase Inhibitor p15
- Cyclin-Dependent Kinase Inhibitor p16 -- metabolism
- Dose-Response Relationship, Drug
- Down-Regulation
- Enzyme Activation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Indoles -- pharmacology
- MAP Kinase Signaling System
- Maleimides -- pharmacology
- Oligonucleotides -- chemistry
- Oligonucleotides, Antisense -- chemistry
- Phosphorylation
- Polymerase Chain Reaction
- Protein Isoforms
- Protein Kinase C -- metabolism
- Protein Kinase C-alpha
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Tetradecanoylphorbol Acetate
- Time Factors
- Transfection
- Tumor Suppressor Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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