Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation. [electronic resource]
Producer: 20050912Description: 26295-302 p. digitalISSN:- 0021-9258
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Apoptosis Regulatory Proteins
- Bcl-2-Like Protein 11
- Blotting, Western
- Butadienes -- pharmacology
- Cell Survival
- Cells, Cultured
- Down-Regulation
- Dual Specificity Phosphatase 6
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Hypoxia
- MAP Kinase Kinase 1 -- metabolism
- MAP Kinase Kinase 2 -- metabolism
- MAP Kinase Signaling System
- Macrophages -- metabolism
- Membrane Proteins
- Mice
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Models, Biological
- Nitriles -- pharmacology
- Phosphoprotein Phosphatases -- metabolism
- Phosphoric Monoester Hydrolases -- metabolism
- Phosphorylation
- Protein Phosphatase 2
- Protein Tyrosine Phosphatases -- metabolism
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Recombinant Proteins -- chemistry
- Serine -- chemistry
- Time Factors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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