The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. [electronic resource]
Producer: 19920422Description: 1687-97 p. digitalISSN:- 0270-7306
- Acute Disease
- Amino Acid Sequence
- Base Sequence
- Chimera -- genetics
- Chromosomes, Human
- Chromosomes, Human, Pair 6
- Chromosomes, Human, Pair 9
- Cloning, Molecular
- Gene Expression Regulation, Neoplastic
- Humans
- Introns -- genetics
- Leukemia, Myeloid -- genetics
- Molecular Sequence Data
- Protein Conformation
- RNA, Messenger -- genetics
- Sequence Homology, Nucleic Acid
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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