RAR-related orphan receptor A isoform 1 (RORa1) is disrupted by a balanced translocation t(4;15)(q22.3;q21.3) associated with severe obesity. [electronic resource]
Producer: 20051207Description: 928-34 p. digitalISSN:- 1018-4813
- Adipocytes -- metabolism
- Adolescent
- Adult
- Base Sequence
- Blotting, Western
- Cells, Cultured
- Chromosome Breakage -- genetics
- Chromosome Mapping
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 4
- Female
- Humans
- Karyotyping
- Male
- Mothers
- Obesity, Morbid -- genetics
- Phenotype
- Receptor Protein-Tyrosine Kinases
- Receptor Tyrosine Kinase-like Orphan Receptors
- Receptors, Cell Surface -- genetics
- Translocation, Genetic -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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