Mycobacterium avium 104 deleted of the methyltransferase D gene by allelic replacement lacks serotype-specific glycopeptidolipids and shows attenuated virulence in mice. [electronic resource]
Producer: 20050927Description: 1262-73 p. digitalISSN:- 0950-382X
- Animals
- Antigens, Bacterial
- Cells, Cultured
- Chemokine CCL5 -- analysis
- Colony Count, Microbial
- Disease Models, Animal
- Gene Deletion
- Genes, Bacterial -- physiology
- Genetic Complementation Test
- Glycolipids -- metabolism
- Glycopeptides -- metabolism
- Liver -- microbiology
- Lung -- microbiology
- Macrophages -- immunology
- Methyltransferases -- genetics
- Mice
- Mycobacterium avium Complex -- enzymology
- Mycobacterium avium-intracellulare Infection -- microbiology
- Tuberculosis -- microbiology
- Tumor Necrosis Factor-alpha -- analysis
- Virulence -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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