Role of the endothelin system in secondary pulmonary hypertension related to air embolism: lessons learned from testing four classes of endothelin blockers in a rat model. [electronic resource]
Producer: 20081103Description: S386-9 p. digitalISSN:- 1533-4023
- Acute Disease
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Atrasentan
- Benzofurans -- pharmacology
- Cardiovascular Agents -- pharmacology
- Disease Models, Animal
- Embolism, Air -- complications
- Endothelin A Receptor Antagonists
- Endothelin B Receptor Antagonists
- Endothelin-Converting Enzymes
- Endothelins -- metabolism
- Hemodynamics -- drug effects
- Hypertension, Pulmonary -- drug therapy
- Male
- Metalloendopeptidases -- antagonists & inhibitors
- Organophosphonates -- pharmacology
- Protease Inhibitors -- pharmacology
- Pyrrolidines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Receptor, Endothelin A -- metabolism
- Receptor, Endothelin B -- metabolism
- Sulfonamides -- pharmacology
- Time Factors
- Ventricular Dysfunction, Right -- drug therapy
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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