DNA damage uncouples the mitogenic response to IGF-I in MCF-7 malignant breast cancer cells by switching the roles of PI3 kinase and p21WAF1/Cip1. [electronic resource]
Producer: 20050824Description: 506-13 p. digitalISSN:- 0020-7136
- Breast Neoplasms -- genetics
- Cell Cycle
- Cell Cycle Proteins -- biosynthesis
- Cyclin-Dependent Kinase Inhibitor p21
- DNA Damage
- DNA Repair
- Female
- Humans
- Insulin-Like Growth Factor I -- physiology
- Mitogens
- Phosphatidylinositol 3-Kinases -- biosynthesis
- Signal Transduction
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- physiology
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Publication Type: Journal Article
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