RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells. [electronic resource]
Producer: 20050811Description: C352-60 p. digitalISSN:- 0363-6143
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid -- pharmacology
- Amides -- pharmacology
- Animals
- Cells, Cultured
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors -- metabolism
- Immunoblotting
- Indoles -- pharmacology
- Intracellular Signaling Peptides and Proteins
- Male
- Maleimides -- pharmacology
- Muscle Proteins -- drug effects
- Muscle, Smooth, Vascular -- drug effects
- Myosin-Light-Chain Phosphatase -- antagonists & inhibitors
- Phosphoproteins -- drug effects
- Phosphorylation -- drug effects
- Protein Kinase C -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Pyridines -- pharmacology
- Rabbits
- Signal Transduction -- physiology
- Thrombin -- pharmacology
- Vasoconstrictor Agents -- pharmacology
- rho-Associated Kinases
- rhoA GTP-Binding Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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