Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. [electronic resource]
Producer: 20050706Description: 5691-6 p. digitalISSN:- 0027-8424
- Binding Sites
- Cell Line, Tumor
- Directed Molecular Evolution -- methods
- Estradiol -- chemistry
- Estrogen Receptor alpha -- chemistry
- Humans
- Ligands
- Models, Molecular
- Molecular Structure
- Mutagenesis, Site-Directed
- Protein Binding
- Protein Engineering -- methods
- Protein Structure, Tertiary
- Random Allocation
- Transcriptional Activation
- Two-Hybrid System Techniques
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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